“Circulating DNA from tumoral origin is characterized by high fragmentation level”
Florent Mouliere, Bruno Robert, Celine Gongora, Anne-Sophie Guedj, Maguy Del Rio, Marc Ychou, Franck Molina, Denis Pezet, and Alain R Thierry.
Sysdiag UMR3145-CNRS/BIO-RAD; 2U896 INSERM-Université Montpellier-CRLC Montpellier IRCM-Institut Recherche en Cancérologie de Montpellier; Centre Régional de Lutte contre le Cancer Val d'Aurelle-Paul Lamarque; and Centre Hospitalier Universitaire de Clermont-Ferrand. France.
“Profile of the circulating RNA in apparently healthy individuals obtained with massive parallel sequencing of total plasma RNA on solid platform”
Dmitry V. Semenov, Dmitry A. Baryakin, Evgeny V. Brenner, Alexander M. Kurilshikov, Gennady V. Vasiliev, Leonid A. Bryzgalov, Elena D. Chikova, Julia A. Fillipova, Elena V. Kuligina, and Vladimir A. Richter.
Institute of Chemical Biology and Fundamental Medicine SB RAS, and Institute of Cytology and Genetics SB RAS. Novosibirsk, Russia.
“Further developments in the use of cell-free fetal DNA for non-invasive prenatal diagnosis of single gene disorders: Digital PCR allows diagnosis of sickle cell disease”
A.N. Barrett, T.C.R. McDonnell, and Lynn S. Chitty.
North East Thames Regional Molecular Genetics Laboratories; Institute of Child Health; and UCLH NHS Foundation Trust. London, UK.
“High throughput sequencing enables non-invasive prenatal diagnosis of beta thalassaemia using SNPs”
Thessalia Papasavva, Wilfred van Ijcken, Chirstel Kockx, Frank G. Grosveld, and Marina Kleanthous.
The Cyprus Institute of Neurology and Genetics. Nicosia, Cyprus.
Erasmus Medical Centre. Rotterdam, Netherlands.
“High levels of circulating exosomes in plasma correlate with shorter survival in human colorectal cancer in a p53/tsap6 independent way”
Marta Rodríguez-Moreno, Vanessa García-Barberán, Francisco Javier Silva-Leal, José Miguel García-Ruiz, Gemma Domínguez-Muñoz, Cristina Peña-Maroto, and Félix Bonilla-Velasco.
Hospital Universitario Puerta de Hierro-Majadahonda. Madrid, Spain.
“Clinical usefulness of plasma telomerase reverse transcriptase mRNA as a tumor marker in prostate cancer”
Francisco Dasí, José Antonio March-Villalba, José María Martínez-Jabaloyas, María José Herrero, J. Santamaría, Manuel Gil-Salom, P. Martínez-Rodes, and Salvador F. Aliño.
FIHCUV/INCLIVA; School of Medicine of the University of Valencia; and Hospital Clínico Universitario de Valencia. Spain.
“The transforming effect of cell-free nucleic acids circulating in the plasma of colorectal cancer patients remains after resection of the primary tumor”
Carolina Domínguez-Berzosa, Dolores C. García-Olmo, Héctor Guadalajara, Luz Vega-Clemente, Mariano García-Arranz, and Damián García-Olmo.
Universidad Autónoma de Madrid, “La Paz” University Hospital, and General University Hospital of Albacete. Spain.
“GC-rich cell-free DNA (GC-cfDNA) activates TLR-, NFkB-, JNK/p38- and IRF-dependent signaling pathways in adipose-derived mesenchymal stem cells (ADMSC)”
O.Chvartatskaya, Svetlana V. Kostjuk, P. Loseva, E. Ershova, Tatiana D. Smirnova, L. Kameneva, Elena M. Malinovskaya, Ludmila N. Lyubchenko, O. Roginko, V. Kur'min and Natalya N. Veiko.
Moscow State Pedagogical University and Russian Academy of Sciences, Moscow, Russia.
“Detection of cell-free DNA, RNA and miRNA in exosomes: New non invasive pregnancy-associated markers?”
M. Coulomb, N. Bonello, C. Formizano, N. Beaufils, J. Courageot, M. Tsochandaridis, F. Dignat-George, J. Gabert, and A. Levy-Mozziconacci.
Unité Inserm 608°, Université de la Méditerranée. Marseille, France.
“Profiling of circulating miRNAs in maternal and umbilical cord serum together with those tissue-based miRNAs in placentas and of preeclampsia pregnant women”
Qi Yang, Jiafeng Lu, Hailing Li, Shenqing Wang, Jing Tu, Qinyu Ge, and Zuhong Lu.
Southeast University. Nanjing, China.
“COLD-PCR: a novel PCR assay for noninvasive prenatal diagnosis of genetic diseases”
Silvia Galbiati, Angela Brisci, Faustina Lalatta, Manuela Seia, G. Mike Makrigiorgos, Maurizio Ferrari, Laura Cremonesi.
San Raffaele Scientific Institute; Fondazione IRCCS´ Granda Ospedale Maggiore; Universitá Vita-Salute San Raffaele; and Diagnostica e Ricerca San Raffaele SpA. Milan, Italy.
Dana-Farber/Brigham and Women´s Cancer Center, Brigham and Women´s Hospital. Boston, MA, USA.
“Nucleosome positioning can help identify DNA fragments with higher abundance in plasma”
Muhammed Murtaza, Y. M. Dennis Lo, and Nitzan Rosenfeld.
Cancer Research UK Cambridge Research Institute, and University of Cambridge. UK.
The Chinese University of Hong, Prince of Wales Hospital. Hong Kong, China. |
The Impact of Low-Frequency Noise on the Content of Low-Molecular-Weight DNA of Blood Plasma
I.N. Vasilyeva and V.N. Zinkin.
St. Petersburg Scientific Research Institute of Phthisiopulmonology St.-Petersburg, Russia; and Scientific Research Institute of Military Medicine, Moscow, Russia
Can plasma DNA monitoring be employed in personalized chemotherapy for patients with advanced lung cancer?
Shiyang Pan, Wenying Xia, Qingqing Ding, Yongqian Shu, Ting Xu, Yan Geng, Yachun Lu, Dan Chen, Jian Xu, Fang Wang, Chun Zhao, Peijun Huang, Puwen Huang, Hongbin Shen, Zhibin Hu and Shan Lu.
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; Cancer Center of Nanjing Medical University, Nanjing, China; University of Massachusetts Medical School, Worcester, MA, USA; and National Key Laboratory for Laboratory Medicine of China.
Early second-trimester serum MiRNA profiling predict gestational diabetes mellitus
Chun Zhao, Jing Dong, Tao Jiang, Zhonghua Shi, Peijun Huang, Ran Huo, Juncheng Dai, Shiyang Pan, Zhibin Hu, Jiahao Sha.
Laboratory of Reproductive Medicine; Nanjing Medical University; The First Affiliated Hospital of Nanjing Medical University; School of public health, Nanjing Medical University; and Nanjing Maternity and Child Health Hospital of Nanjing Medical University. Nanjing, China.
Evaluation of BD vacutainer EDTA-K2 plus tubes with and without polymer gel for plasma DNA quantification
Dan Chen, Shiyang Pan and Peijun Huang.
The First Affiliated Hospital of Nanjing Medical University and National Key Laboratory for Laboratory Medicine of China. Nanjing, China.
Investigation of methylation patterns of APC gene in lung cancer with a novel fluorescence melting curve analysis assay
Li Gao, Shiyan Pan, Yongqian Shu, Lixia Zhang, Erfu Xie and Peijun Huang.
The First Affiliated Hospital of Nanjing Medical University , Nanjing 210029, China; The First Affiliated Hospital of Nanjing Medical University and National Key Laboratory for Laboratory Medicine of China. Nanjing, China.
Can mycobacterium tuberculosis DNA be detected in plasma/serum samples from tuberculosis patients?
Bing Gu, Shiyang Pan, Hong Wang, Zihe Yan, Chun Zhao and Genyan Liu.
The First Affiliated Hospital of Nanjing Medical University and National Key Laboratory for Laboratory Medicine of China. Nanjing, China.
Characterization of H3K9me3- and H4K20me3-associated Circulating Nucleosomal DNA by High-Throughput Sequencing in Colorectal Cancer
Ugur Gezer, Duran Üstek, Ebru E. Yürüker, Aris Cakiris, Neslihan Abaci, Stefan Holdenrieder and Nejat Dalay.
Istanbul University Oncology Institute, Department of Basic Oncology, Istanbul, Turkey; Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey; and Institute of Clinical Chemistry and Pharmacology, University of Bonn, Bonn, Germany.
Circulating nucleic acids in plasma for biomarker development in oncology and neurodegenerative diseases.
A. Melnikov and V. Levenson.
Department of Radiation Oncology, Rush University Medical Center, Chicago, IL, USA
The final hurdle-When Is Non-Invasive Prenatal Diagnosis Cost-Effective?
Ala Szczepura and Leeza Osipenko
Warwick Medical School, University of Warwick. Coventry, UK.
Role of extracellular dna OXydative modification in radiation induced bystander effects in human endotheliocytes
A.Yu. Alekseeva, S.V. Kostyuk, T.D. Smirnova, A. Baranova, O. A. Roginko, V. A. Kuzmin and N.N.Veiko.
Research Center for Medical Genetics, Central Clinical Hospital and Institute of Biochemical Physics. Moscow, Russia.
Quantification of free-circulating DNA in plasma of respiratory patients: NSCLC versus chronic inflammation
Adam Szpechcinski, Krystyna Maszkowska-Kopij, Wlodzimierz Kupis,Elzbieta Puscinska, Jolanta Zaleska, Elzbieta Radzikowska, Tadeusz Orlowski,Pawel Sliwinski, Kazimierz Roszkowski-Sliz and Joanna Chorostowska-Wynimko.
National Institute of Tuberculosis and Lung Diseases. Warsaw, Poland.
Methylation status of RASSF1A and RARβ2 genes in the circulating DNA from lung cancer patients’ blood
Anastasia
A. Ponomaryova, Еlena Yu. Rykova, Nadezhda V. Cherdyntseva, Tatiana E. Skvortsova, Аlexey Yu. Dobrodeev, Alexander A. Zav’yalov, Sergey A. Tuzikov,
Valentin V. Vlassov and Pavel P. Laktionov.
Cancer Research Institute, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia. Institute of Chemical Biology and Fundamental Medicine, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia.
Isolation and genetic characterisation of circulating cell-free
fetal DNA for non-invasive prenatal diagnosis
Ciara O'Sullivan, Teresa Mairal, Klaus S.Drese, Regina Preywisch and Thessalia Papasavva.
Universitat Rovira I Virgili, Tarragona, Spain. Institut für Mikrotechnik Mainz GmbH, Mainz, Germany. The Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.
Storage conditions of cDNA from human plasma samples affect the output of real-time PCR
María G. Picazo and Dolores C. García-Olmo.
General University of Albacet. Albacete, Spain.
The altered profile of seminal plasma microRNAs in infertile men: a novel tool in the molecular diagnosis of male infertility
Cheng Wang, Cuihua Yang, Xi Chen, Bing Yao, Junjun Wang, Xiaojun Li, Yong Shao, Junfeng Zhang, Ke Zen, Chen-Yu Zhang and Chunni Zhang
Jiangsu Engineering Research Center for microRNA Biology and Biotechnology, School of Life Sciences, Nanjing University; and Jinling Hospital, Clinical School of Medical College, Nanjing University. Nanjing, China.
Kinetic of the releasing of cell-free DNA and RNA, mutated and non-mutated, into the bloodstream during tumor progression in rats
Dolores C. García-Olmo, María G. Picazo, Inmaculada Toboso and Damián García-Olmo.
General University Hospital of Albacete, Albacete, Spain; “Ramón y Cajal” University Hospital, Madrid, Spain; Universidad Autónoma de Madrid, Spain; and “La Paz” University Hospital, Madrid, Spain.
NIH-3T3 fibroblasts cultured with plasma from colorectal cancer patients generate poorly differentiated carcinomas in mice
Carolina Domínguez, Elena Collantes, Héctor
Guadalajara, Damián García-Olmo and Dolores C. García-Olmo.
General University Hospital of Albacete, Albacete, Spain; Universidad Autónoma de Madrid, Spain; and “La Paz” University Hospital, Madrid, Spain.
Plasma cell-free DNA levels after severe traumatic brain injury and during the next 96 hours of follow up
Hada Macher, Juan J Egea, Elena Gordillo-Escobar, Jaume Revuelto-Rey,
Judy Enamorado-Enamorado, Patrocinio Molinero, Juan M Guerrero, José Mª
Dominguez, Francisco Murillo and Amalia Rubio.
University Hospital “Virgen del Rocío”. Seville, Spain.
A further improvement in quantifying male fetal DNA in maternal plasma
Shengnan Jin, Xueqin Michelle Lin and Chunming Ding.
KK Women´s and Children´s Hospital, Singapore.
LOH proximal to M6P/IGF2R locus in circulating DNA of ovarian cancer patients correlates with prognosis
Jan Dominik Kuhlmann, Heidi Schwarzenbach, Pauline Wimberger, Martin
Heubner, Micaela Poetsch, Rainer Kimmig and Sabine Kasimir-Bauer.
University of Duisburg-Essen, Essen, Germany; University Medical Center Hamburg-Eppendorf, Germany; and University Hospital of Duisburg-Essen, Essen, Germany.
Promotors of immune response genes are differentially methylated in cfDNA of hemodialyzed patients
Marie Korabecna, Eva Pazourkova, Ales Horinek, Magdalena Mokrejsova and Vladimir Tesar.
Charles University, Prague, Czech Republic; and Charles University, Pilsen, Czech Republic.
Clinical evaluation of the mutational status, concentration and fragmentation index with a novel multiplex test for the analysis of circulating DNA in the context of the colorectal cancer
Florent Mouliere, Celine Gongora, Bruno Robert, Maguy del Rio, Fanny Rolet, Franck Molina, Evelyne Crapez, Pierre-Jean Lamy, Denis Pezet, Muriel Mathonnet, Marc Ychou and Alain R. Thierry.
Sysdiag UMR3145 - CNRS / BIO-RAD; U896 INSERM-Université Montpellier1- IRCM-Institut Recherche en Cancérologie de Montpellier; Centre Régional de Lutte contre le Cancer Val d'Aurelle-Paul Lamarque, Montpellier, France ; CHU Estaing Clermont-Fd; CHU Limoges, Limoges, France ; and Centre Régional de Lutte contre le Cancer Val d'Aurelle-Paul Lamarque, Montpellier, France.
Non-invasive prenatal determination of fetal gender and single-gene disorder from plasma of pregnant women
Akihiko Sekizawa, Junko Yotsumoto, Asami Fukuda, Kiyotake Ichizuka, Keiko
Koide and Takashi Okai.
Showa University. Tokyo, Japan
Non-invasive prenatal assessment of fetal sex by nucleic acid analysis in maternal plasma
Aggeliki Kolialexi, Georgia Tounta, Christina Vrettou, Nikolas Papantoniou, Aris Antsaklis and Ariadni Mavrou.
Athens University School of Medicine. Athens, Greece.
Apoptosis is an essential event to mediate the stress-signalisation factors formation in irradiated lymphocytes in radiation-induced bystander effect
M.S. Konkova, A.V. Ermakov, L.V. Efremova, S.V. Kostyuk and N.N. Veiko
Research Centre for Medical Genetics, Russian Academy of Medical Sciences. Moscow, Russia
Identification of gastric cancer associated microRNAs in plasma of gastric cancer patients on microRNAs microarray
Daisuke Ichikawa, Shuhei Komatsu, Hirotaka Konishi, Masahiro Tsujiura, Hiroki Takeshita, Ryo Morimura, Hiroaki Nagata, Tomohiro Arita, Shoji Hirajima, Tsutomu Kawaguchi, Atsushi Shiozaki and Eigo Otsuji.
Kyoto Prefectural University of Medicine. Kyoto, Japan.
Diagnosis by high resolution melting in serum cell-free DNA of MEN2A: Towards prenatal diagnosis
Hada C. Macher, María A. Martínez-Brocca, Amalia Rubio, Patrocinio Molinero, Cristina León-García, Elena Navarro-González and Juan M. Guerrero.
“Virgen del Rocío” University Hospital (IBiS/CSIC/SAS/University of Seville). Seville, Spain.
Feasibility of non-invasive fetal RHD and SRY determination into clinical
routine using a Multiplex RT-PCR assay for cell-free DNA in pregnant women plasma
Hada C. Macher, Pilar Noguerol, Amalia Rubio-Calvo, Patrocinio Molinero, Pablo Medrano-Campillo, Manuela Alaya, José A. Pérez-Simán and Juan M. Guerrero.
Departments of Clinical Biochemistry and Hematology and Hemotherapy, The “Virgen del Rocío” University Hospital (IBiS/CSIC/SAS/University of Seville). Seville, Spain.
Circulating miRNAs as biomarkers in ovarian Cancer
M. Vila, J. Vigara and R. León.
Facultad de Ciencias Experimentales. University of Huelva. Huelva. Spain.
Oxidative modifications of DNA alter its biological action on rat neurons
K.V.Glebova, I.L.Konorova, A.V. Marakhonov, I.V.Barskov, L.G.Khaspekov, N.N.Veiko
Research Centre for Medical Genetics and Research Center of Neurology, Russian Academy of Medical Sciences. Moscow, Russia.
Circulating nucleic acids: Pre-analytical stabilization in blood and
automated large-volume extraction for diagnostic applications
Martin Horlitz, Annabelle Schubert, Annette Nocon, Simone Graf and Markus Sprenger-Haussels.
QIAGEN GmbH. Hilden, Germany.
C-rich fragments of cell-free DNA (cfDNA) induce an adaptive response (AR) in human adipose-derived mesenchymal stem cells (MSC)
E. Malinovskaya, V. Shubin, S. Kostjuk, P. Loseva, T. Smirnova, L. Kameneva L, L. Ljubchenko, A. Karpukhin and N. Veiko N.
Research Centre for Medical Genetics and Blokhin Cancer Research Center, Russian Academy of Medical Sciences. Moscow, Russia.
Cell-free DNA (cfDNA) from cancer cell cultivation medium upregulates PPARG2 expression in adipose-derived mesenchymal stem cells (ADMSC)
P. Loseva, S. Kostjuk, N. Clement, C. A. Dechesne, C. Dani, T. Smirnova, L. Kameneva, L. Ljubchenko and N. Veiko.
Research Centre for Medical Genetics, Russian Academy of Medical Sciences,
Moscow, Russia; Institute of Developmental Biology and Cancer, Faculty of Medicine, University of Nice Sophia-Antipolis, CNRS, Nice; and Blokhin Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia.
“Fetal” exosomes: the way of non invasive prenatal diagnosis?
L. Nasca, M. Tsochandaridis, L. Hajun, A. Levy-Mozziconacci.
Marseille’s Hospital, Université de la Méditerranée, France.
Quantification of fetal and total cell-free DNA in maternal circulation : relationships with fetal or materno-fetal disorders
F. Lombardini, M. Tsochandaridis, L. Nasca, C. Toga, C. D’ercole, F. Bretelle, L. Boubli, J. Gabert and A. Levy-Mozziconacci.
Marseille’s Hospital, Université de la Méditerranée, France.
Routine fetal RHD genotyping in maternal plasma in first trimester: a two year experience in south of France
M. Tsochandaridis, A. Ben Lassoued, L. Nasca, N. Burles, M. Elbaz, J. Gabert and A. Levy-Mozziconacci.
Marseille’s Hospital, Université de la Méditerranée, France.
Mass Spectroscopic analysis of Microvesicles in Blood and Urine of healthy and prostate cancer patients
Wilfred G. Chen.
Carlton Centre. San Fernando, Trinidad, West Indies.
Comparative study of apoptotic and genomic DNA using massive parallel sequencing
E.S. Morozkin, E.M. Loseva, I.V. Morozov, A.M. Kuril’shikov, A.A. Bondar, V.V. Vlassov and P.P. Laktionov.
Institute of Chemical Biology and Fundamental Medicine, SD RAS. Novosibirsk, Russia.
The first author of this work received one of the two awards for
the best communications presented by young researchers
DNA microchimerism in peripheral blood of dyzigotic twins
Levente Lazar and Balint Nagy.
Semmelweis University Budapest. Budapest, Hungary.
Circulating tumor-specific DNA: A biomarker for screening and prognostic factor in breast cancer
J. Martínez-Galán, B. Torres-Torres, J.R. Delgado, R. Del Moral, J. López-Peñalver, S. Ríos-Arrabal, and M.I. Núñez.
“Virgen de las Nieves” University Hospital; Biomedical Research Center; and Radiobiology Department of Medicine University. Granada, Spain
Novel diagnostic value of circulating miR-18a in plasma of patients with gastric cancer.
Masahiro Tsujiura, Shuhei Komatsu, Daisuke Ichikawa, Shoji Hirajima, Ryo
Morimura, Hirotaka Konishi, Hiroki Takeshita, Tomohiro Arita, Tsutomu Kawaguchi,
Hiroaki Nagata, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto and Eigo Otsuji.
Kyoto Prefectural University of Medicine. Kyoto, Japan
Investigation of plasma lncRNA levels in chronic lymphocytic leukemia and multiple myeloma patients
Mustafa Isin, Emre Ozgur, Melih Aktan, Nilgun Erten, Ugur Gezer and Nejat Dalay.
Istanbul University Oncology Institute and Istanbul University Medical Faculty. Istanbul, Turkey.
Inhibition of dsRNA-induced immune response by ODN analogs of circulating DNA
Anna V. Cherepanova, Maria V. Kharkova, Peter V. Pogrebnoy, Valentin V.
Vlassov and Pavel P. Laktionov.
Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia. R. E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, NAS, Kyiv, Ukraine.
Assessment of serum microRNAs in receptor-negative and positive breast cancer patients before and after chemotherapy
Corinna Eichelser, Dieter Flesch-Janys, Jenny Chang-Claude, Klaus Pantel and Heidi Schwarzenbach.
University Medical Center Hamburg-Eppendorf, Hamburg, Germany; and German Cancer Research Center, Heidelberg, Germany.
Tumor-derived extracellular DNA as factor affecting primary cell methylation
T.E. Skvortsova, A.O. Lebedeva, E.S. Morozkin, V.V. Vlassov and P.P. Laktionov.
Institute of Chemical Biology and Fundamental Medicine. Novosibirsk, Russia.
Novel diagnostic value of circulating miR-18a in plasma of patients with esophageal squamous cell carcinoma
Shoji Hirajima, Shuhei Komatsu, Daisuke Ichikawa, Hiroki Takeshita, Masahiro Tsujiura, Ryo Morimura, Hirotaka Konishi, Tomohiro Arita, Tsutomu Kawaguchi, Hiroaki Nagata, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto and Eigo Otsuji.
Kyoto Prefectural University of Medicine, Kyoto, Japan
Facilitating implementation of NIPD: a modified protocol to detect the
universal fetal DNA marker RASSF1A
E. White, C. L. Dent, V. J. Hall, J. A. Crolla and L. S. Chitty
National Genetics Reference Laboratory (Wessex), Salisbury NHS Foundation Trust,Salisbury, UK; UCL Institute of Child Health, London, UK; and UCLH NHS Foundation Trust, London, UK.
Efficacy of bisulfite modification and DNA recovery in clinical samples with minute amounts of circulating DNA
Olga E. Bryzgunova, Pavel P. Laktionov, Tatyana E. Skvortsova, Anna A. Bondar, Evgeniy S. Morozkin, Alena O. Lebedeva, Valentin V. Vlassov, Kurt Miller and Hans Krause.
Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia; and Charite-Universitatsmedizin Berlin, Campus Mitte (CCM), Department of Urology, Berlin, Germany.
Free circulating DNA: an objetive severe preeclampsia marker to monitorize Patients who could suffer hellp syndrome
Alzenira de Fátima Costa, Hada C. Macher, Rafael Moreno Luna, María Luisa
Miranda, Lucas Cejillo, Rafael Torrejón, José Vilar and Juan M. Guerrero.
“Virgen del Rocío” University Hospital/Institute of Biomedicine of Seville, Spain.
Clinical use of NIPD for monogenic disorders: patient perspectives &
decision-making
S. Perlado, A. Bustamante-Aragonés, M. Martínez, MJ Trujillo-Tiebas, J.
Plaza, M. Rodríguez de Alba and C. Ramos.
Fundacion Jimenez Diaz, Madrid, Spain.
Assessment of diabetic retinopathy by measuring Retina specific mRNA in blood
Mohammad Salman Ahmad, A.Butt, J.Powrie and R.Swaminathan.
St. Thomas' Hospital. London, UK.
Circulating microRNAs in the assessment of heart failure and microRNA-133a as a potential biomarker of cardiac remodelling
E. C. Fung, A. Butt, G. Carr-White and R. Swaminathan.
St Thomas' Hospital. London, UK.
Circualting microRNA in diabetic nephropathy
H. Moussa, L.Gnudi, A.Butt and R.Swaminathan
St. Thomas' Hospital. London, UK.
Circulating mRNA in salt sensitivity
E. Jennison, A. Butt, K. Connell, P. Chowienczyk and R. Swaminathan.
St. Thomas' Hospital. London, UK.
Routine antenatal determination of fetal rhesus (rh) d status using cell free fetal dna in the maternal circulation in early pregnancy
L.S. Chitty, G. Daniels, K. Finning, E. Massey, C. J. Phillips and P. Soothill.
UCL Institute of Child Health and UCLH NHS Foundation Trust, London, UK; International Blood Group Reference Laboratory, NHS Blood and Transfusion, Bristol, UK; Swansea University, Wales, UK; and University of Bristol & St Michael’s Hospital, United Bristol Health Care Trust, Bristol, UK.
Circulating kidney specific mRNA in diabetic nephropathy
Young Mee Choi, A. Butt, L. Gnudi and R. Swaminathan.
St. Thomas' Hospital. London, UK.
Biological activity of virtosomes released by stimulated and non-stimulated lymphocytes.
MP. Viola-Magni, A. Sesay, S. Cataldi, P. B. Gahan and M. Stroun.
University of Perugia, Italy; King’s College, London, UK; and OncoXL, Geneva, Switzerland.
Circulating tumour DNA as a non-invasive tool for monitoring ovarian cancer dynamics
Nitzan Rosenfeld, Davina Gale, Christine Parkinson, Anna Piskorz, Tim Forshew, Dana Tsui, Muhammed Murtaza and James D. Brenton.
Cancer Research UK Cambridge Research Institute, Cambridge, UK; and University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
The first author of this work received one of the two awards for
the best communications presented by young researchers
Development of mutation-specific PCR-based techniques for detection of minute quantities of mutant DNA in a huge background of wild-type DNA with application to mutation hotspots in KRAS and BRAF genes
Andrey R. Zaretsky.
Shemyakin-Ovchinnikov Institute for Bioorganic Chemistry, Russian Academy of Sciences; and Evrogen Lab Ltd. Moscow, Russia.
Implementing non-invasive prenatal diagnosis for genetic disorders using cell free fetal DNA into clinical practice: Acceptability and impact on pregnancy management
M. Hill, A. Barrett, C. Meany, N. Lench and L.S. Chitty.
Great Ormond Street Hospital for Children and UCL Institute of Child Health and UCLH NHS Foundation Trust. London, UK.
Transfection of non-tumor host’s cells during tumor progression. An experimental study in nude mice
Dolores C. García-Olmo, María G. Picazo, Mónica-Gómez Juárez, Damián García-Olmo.
General University Hospital of Albacete, Universidad Autónoma de Madrid and “La Paz” University Hospital. Spain.
Circulating MicroRNAs in plasma of patients with esophageal squamous cell carcinoma
Shuhei Komatsu, Daisuke Ichikawa, Hiroki Takeshita, Masahiro Tsujiura, Shoji
Hirajima, Tsutomu Kawaguchi, Tomohiro Arita, Hiroaki Nagata, Ryo Morimura, Hirotaka Konishi, Atsushi Shiozaki, Hitoshi Fujiwara, Kazuma Okamoto and Eigo Otsuji.
Kyoto Prefectural University of Medicine. Kyoto, Japan.
Novel Diagnostic Value of Circulating miR-18a in Plasma of Patients
with Pancreatic Cancer
Tsutomu Kawaguchi, Shuhei Komatsu, Daisuke Ichikawa, Ryo Morimura Hiroki
Takeshita, Masahiro Tsujiura, Hiroaki Nagata, Hirotaka Konishi, Tomohiro Arita,
Shoji Hirajima, Atsushi Shiozaki, Hisashi Ikoma, Kazuma Okamoto, Toshiya Ochiai and Eigo Otsuji.
Kyoto Prefectural University of Medicine. Kyoto, Japan.
Altered serum microRNA expression profile in patients with astrocytoma: Potential biomarker for diagnosis, classification and prognosis of astrocytoma
Chunni Zhang, Cuihua Yang, Cheng Wang, Xi Chen, Junjun Wang, Yanni Zhang, Xiaojun Zhou, Nanyun Li, Ke Zen and Chen-Yu Zhang.
Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing; School of Life Sciences, Nanjing University, Nanjing; Cancer Hospital of Xuzhou, Xuzhou. China.
Routine fetal RHD genotyping in maternal blood
Antoni Borrell, Maribel Grande, Roser Febrero, A. Payaró, N Dominguez, E. Castellanos, J. Xandri, A Vilallon, Irene Teixidó and Vincenzo Cirigliano.
Institute of Gynecology, Obstetrics and Neonatology, Hospital Clínic Barcelona; Institut Català de la Salut; General Lab, S.A. Barcelona, Spain.
Circulating nucleosomes and Biomarkers of immunogenic cell death as predictive and prognostic markers in cancer patients undergoing local cytotoxic therapy
Yvonne N Fehr, Dorothea Nagel, Christin Wittwer, Ralf-Thorsten Hoffmann, Klaus Tatsch, Tobias Jakobs, Petra Stieber and Stefan Holdenrieder.
Institute of Clinical Chemistry; Institute of Clinical Radiology; University-Hospital Munich-Grosshadern; Municipial Hospital Karlsruhe; University Hospital Bonn. Germany.
Cell-free DNA in plasma and serum indicates disease severity and prognosis in trauma patients
Juliane Rössner, Dorothea Nagel, Konrad Wolf, Jürgen Durner, Jürgen Hallbach, Walter Hofmann, Stefan Margraf,
Martin Scholz, Eduard F Höcherl, Stefan Holdenrieder.
University Hospital Munich, University Hospital Bonn, Hospital Munich-Schwabing, Leukocare. Munich, Germany.
Relevance of plasma DNA integrity in breast cancer patients undergoing neoadjuvant chemotherapy
Julia Lehner, Oliver J. Stötzer, Debora Fersching, Dorothea Nagel, Stefan Holdenrieder.
Institute of Clinical Chemistry, University Hospital Munich-Grosshadern; Hematology/Oncology Outpatient Center Munich; and Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn. Germany.
Are mesenchymal stem cells susceptible to be transformed by tumor cell-free nucleic acids?
Mariano García-Arranz, Carolina Domínguez-Berzosa, Héctor Guadalajara, Dolores C. García-Olmo and Damián García-Olmo.
General University Hospital of Albacete, Universidad Autónoma de Madrid and “La Paz University Hospital”. Spain.
Multiplex massively parallel sequencing for noninvasive prenatal diagnosis
B. H. W. Faas, L. E. L. M. Vissers, I. M. Janssen, J. de Ligt, A. Eggink, J.M.G van Vugt, J. A. Veltman and A. Geurts van Kessel.
Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
Cancer progression mediated by horizontal gene transfer. An in vitro and in vivo study.
C. Trejo-Becerril, E. Pérez-Cárdenas, L. Taja-Chayeb and A. Dueñas-González.
Instituto de Investigaciones Biomédicas, UNAM/Instituto Nacional de Cancerología, México City, México.
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